Vision Loss

We all know that as we age, our eyesight can deteriorate, leading to vision loss (and needing glasses). However, as you can expect, genetics can also play a role in this process. Certain genes have been associated with vision loss, including those involved in developing and maintaining the retina (the part of the eye responsible for detecting light and colour).

One such gene is the ABCA4 gene, which codes for a protein involved in transporting waste products out of the retina. Mutations in this gene can lead to a build-up of toxic substances in the retina, causing damage and vision loss over time. Another gene, called ELOVL4, is involved in producing a type of fat called very long-chain fatty acids, which are essential for the retina's health. Mutations in these two genes can lead to a form of early-onset vision loss known as Stargardt macular degeneration.

Stargardts is the most common form of juvenile macular degeneration.

It is estimated that Stargarts affects 1 in 8 000-10 000 people.

While genetics can play a role in vision loss (in some cases it is purely genetic, like Stargarts), it's important to remember that lifestyle factors such as diet, exercise, and exposure to sunlight can also impact our eye health. Regular eye exams and a healthy lifestyle can help prevent or slow the progression of vision loss, even in those with a genetic predisposition.

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